Kronicles
"THE #1 KING KLICK NEWSOURCE!"
Wednesday, April 16, 2014

Search form

Marijuana Research: CBD Cannabinoid – A New Therapy For Skin Diseases?

Phytocannabinoids, Skin Diseases and You…

Being the largest organ on your body your skin helps to moderate the body’s temperature, and protects us from infections. Sometimes your skin is flaky – sometimes it’s just itchy. No matter what the condition, skin diseases can adversely affect your appearance, creating embarrassing situations and festering low self-esteem. Now, thanks to a new study recently published by the British Journal of Pharmacology – marijuana’s miracle cannabinoids have been shown to play a beneficial role in the treatment of many skin diseases.

“A role for endocannabinoid signaling has been reported in the control of epidermal physiology, whereby anandamide is able to regulate the expression of skin differentiation genes through DNA methylation. Here, we have investigated the possible epigenetic regulation of these genes by selected phytocannabinoids, plant-derived cannabinoids holding potential as novel therapeutics for various human diseases.”

For this study the effects marijuana’s cannabinoids; cannabidiol [CBD], cannabigerol [CBG] and cannabidivarin were scrutinized in human keratinocytes (HaCaT cells), searching for the expression of skin differentiation genes keratins, and on DNA methylation of keratin 10 gene. Additionally, any changes encouraged by phytocannabinoids in global DNA methylation.

The management of infected HaCaT cells with the CBD cannabinoid [cannabidiol] or  CBG [cannabigerol] dramatically minimized the expression of all genes tested via increased DNA methylation for keratin 10 gene.

Concluding that; “phytocannabinoids cannabidiol and cannabigerol as transcriptional repressors that can control cell proliferation and differentiation, suggesting (especially for cannabidiol) a possible exploitation as lead compounds to be used in the development of novel therapeutics for skin diseases.”

source:

Category:  The Ganja Report

Share

Speak Your Mind...

Tweet Nuggs

therealdloc: The sky is blue, hills are green..the vibes are positive..life's good.. Happy & healthy is the way enjoy this... http://t.co/zEi8RoB2j5
TheDirtball: Potatoes, carrots, arugula, and onion bulbs are all in. Purple basil, cilantro, and dill on deck inside.
therealdloc: Here's another one..I can go on for days...I will stop here..when you work hard , live on the road an represent... http://t.co/TXHKKD82U1
therealdloc: How big is your logo been tattooed on some skin..prop's to this homie....#respect... #kmkfam #kmkdloc... http://t.co/qknI0FzlXp
kottonmouth: Buddah Fest 4/19 Orange County, CA http://t.co/HdyGNK6zGz
therealdloc: What up!!! Just got done having some lunch!!! Guess were? Haha!! Had some good conversation with @solistek ,... http://t.co/7lgk412TDD